Finished Products
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Estreva® Gel
Estrogens & progesterones and related Agents


Correction of estrogen deficiencies due natural or surgical menopause:
vasomotor flushes, trophic genito-urinar atrophy, sleeping disorders, emotional disturbance, osteoporosis



ESTREVA® Gel is presented in tube-bottle with dosing pump. Each dose delivers 0.5 g of gel, i.e. 0.5 mg of estradiol.
The average dose is 1.5 g of gel per day, i.e. 3 doses, for 24 to 28 days. The dosage can be adapted to particular needs, or any residual estrogen production and individual pharmacokinetic
characteristics. The dosage may be readapted after 2 or 3 treatment cycles, depending on the clinical symptomatology, in other words : - The dose can be reduced should symptoms of
hyperestrogenia, such as painful breasts, abdominal, pelvic swelling, anxiety, tension, aggressiveness occur. - The dose can be increased should hypoestrogenic symptoms occur, such as
persistence of hot flushes, vaginal dryness, headaches and problems with sleeping, asthenia, tendency for depression. It is highly recommended that a progestogen be combined for the last
12 to 15 days of use of estradiol gel. The patient applies the gel onto clean skin, preferably after washing in the morning or evening, on the abdomen, thighs, arms, shoulders,... with the
exception of the breasts. The gel should not be applied to the mucosa. Massage is of no use but a waiting time of 2 minutes is recommended before putting on clothes. The gel does not
cause staining.




Development Marketing Dept(Product information)